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Her doctor reportedly told her that her binge eating and weight problems were "100% because [she] went on Ozempic." A 2025 review in eClinicalMedicine revealed that a substantial percentage of individuals with obesity who stop taking GLP-1s end up with larger waistlines and higher body mass indexes (BMIs) within 12 weeks

(2016) has shown that when patients receive GLP-1 therapy, there may be reduced activation in brain regions associated with reward processing and motivation when viewing high-calorie food images compared to baseline or placebo conditions

Supply issues Making the GLP-1 drug is a multi-step process, which is slow and capital-intensive

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Dizziness or lightheadedness occurs in roughly 8% to 10%, often related to reduced food intake, dehydration, or blood pressure changes from weight loss