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Using a Xenopus egg-extract model, which uncouples DNA repair from gene transcription 26 , we determined that IDH1 inhibition increased DSB formation and decreased HR, which was rescued by KG (Fig

The suitable chemical agent used for induction can be selected from IPTG (isopropylthiogalactoside), SUBSTITUTE SHEETS (RULE 26) tryptophan, nalidexic acid, oxalinic acid, nitrogen or sugars analogs

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Think of these as frameworksstarting points for designing your own rigorous experiments

This article explores the mechanistic differences , the neurobiology of reward , and the research context in a way that is evidence-informed, nuanced, and appropriate for scientific and educational discussion

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