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In Studies 2, 3, 5, 7, 8 and 9, all patients received instruction for a reduced-calorie diet (approximately 500 kcal/day deficit) and increased physical activity counseling (recommended to a minimum of 150 min/week) that began with the first dose of study medication or placebo and continued throughout the trial
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Genetics may play a small part in this
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doi: 10.1128/AAC.02167-19
Beyond their role in addiction, GLP-1 receptor agonists are used in a range of medical conditions, including type 2 diabetes, obesity, cardiovascular disease, liver and kidney health, and emerging research in neurodegenerative disorders
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