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Elevated LDH, associated with a dismal prognosis in many solid tumors (Zhang et al., 2015), is mitigated by ISOs reported selective inhibition of the PI3K-AKT-mTOR pathway

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A-GSH targeting resulted in a time-dependent increase in the cellular internalization of 3-PLGs conjugated with active agents (Figs

Discontinue and reassess if shedding seems disproportionate to expected adjustment

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