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The protective effect of SFN appears to be NRF2-dependent, as NRF2 deficiency exacerbated psoriasis-like symptoms, as well as the inflammatory response and abnormal proliferation of keratinocytes in the mice, and SFN had little therapeutic effect in the IMQ-modeled knockout mice

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There is a theoretical case for using both in certain patients, targeting different physiological mechanisms simultaneously, though this approach is under evaluation and not yet standard of care

Package Quantity: 10-pack Skin Type: Normal, Dry, Combination, and Oily Skincare Concerns: Dullness, uneven texture and dryness HOW TO USE Suggested Usage Unfold the mask Apply the mask to clean, dry skin Leave on for five minutes Remove the mask and massage any excess product into the skin

By encouraging melanin production, vitamin C can help reduce the appearance of dark spots and uneven skin tone