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Concisely, AEECC at the doses 250 and 500 mg/kg revoked stimulated CYP nociception, bladder weight and serum V.P., edema and hemorrhage, NO, IL-6 and tumor necrotic factor-alpha levels in the sample and showed significant anti-nociceptive and anti-inflammatory results

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World J Gastroenterol 2012

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Serious adverse effects have not been widely reported, but long-term safety data in humans is lacking