[15] Methionine donates methyl groups for the synthesis of S-adenosyl-methionine, which in turn drives phosphatidylcholine production and very-low-density lipoprotein assembly, facilitating export of triglycerides from hepatocytes and mitigating diet-induced steatosis
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They're often paired in research because they hit the same biological pathways from different angles
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Am J Physiol Lung Cell Mol Physiol 310(9):L837L845 Nie Z, Jacoby DB, Fryer AD (2014) Hyperinsulinemia potentiates airway responsiveness to parasympathetic nerve stimulation in obese rats
Human RCT-level proof does not yet exist, and the FDA has explicitly cautioned against compounded formulations