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"The Brain Hepatocyte Growth Factor/c-Met Receptor System: A New Target for the Treatment of Alzheimer's Disease." Journal of Alzheimer's Disease
The greater decrease in LAC levels in severe forms of MDD and in patients with treatment resistant depression (TRD) is akin to a kindling-like progression of depression in that earlier age at onset and/or the presence of early life adversity, such as emotional trauma, conveys liability to more severe and treatment-resistant course of illness [51, 53, 55]
Additionally, some proteins, such as ferritin, transferrin, lactoferrin, caeruloplasmin, act as antioxidants, binding and sequestering transition metals that may start oxidative reactions
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the meaningful tissue and body-composition changes in this class generally unfold over roughly six months
