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Correcting a true B12 deficiency can improve energy and exercise capacity, which may indirectly help with diet and training
Peer review Peer review information Nature Medicine thanks Christiana Kartsonaki, Peter Rossing, Naveed Sattar and Vikas Sridhar for their contribution to the peer review of this work
In mechanistic terms, 5-Amino-1MQ is studied as a means of conserving cellular SAM and NAD that would otherwise be consumed by NNMT activity a pathway of interest in energy-metabolism and adipose-tissue research
B12 injections bypass the gastrointestinal tract and are 100% bioavailable, making them ideal for patients with pernicious anemia, GI disorders, or severe deficiency
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