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Cell death (CD) is essential for maintaining homeostasis and basic biological functions within tissues, and its changes are of great importance in disease pathology

In December 2024, NICE recommended the use of tirzepatide (Mounjaro), alongside semaglutide (Wegovy) and liraglutide (Saxenda), for the treatment of weight-related comorbidities.10 NICE recommended these drugs alongside diet and exercise, yet many patients lack structured programs offering nutritional, behavioural, and psychological support

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87%, respectively), and in the subgroup of children with developmental delay, cerebral palsy, and intellectual disability the percentage of failure after Mel was higher ( Both Mel and Dex were safe to use and none of the participants experienced any significant side effects

GIP, Gastric inhibitory polypeptide

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