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Hyperglycemia Diabetes is associated with the accelerated disappearance of capillary endothelium [159], morphological and functional alterations of ECs [160], and the weakening of intercellular junctions [161], which ultimately leads to ECD

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Over time, peptides can begin to break down, which may lead to reduced effectiveness in supporting weight loss goals

Nature 575:688692

2023;58:1383-1398 e1386