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At baseline, the patient had class III obesity with a weight of 117.72 kg (259 lb) and was initiated on tirzepatide 2.5 mg once weekly in June 2022 to assist with weight loss
Once usage stops, melanin levels may gradually return to normal, causing skin tone to revert over time, especially with sun exposure
Expensive ($400-1,500/month without insurance)
During each injection, press and hold the dose button for the full time as stated in the instructions so all of the medication is delivered
Framingham, SCORE, and DECODE risk equations do not provide reliable cardiovascular risk estimates in type 2 diabetes
The company also withdrew a Phase 2 study of alternative injection devices for CagriSema in type 2 diabetes, announced on 7 July 2026
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