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6+ months Significant weight reduction, often 1520% of body weight when combined with lifestyle changes

Many pills, powders, and protein shakes claim to aid in various health functions

This cardiac effect, attributed primarily to the glucagon receptor activation, is one of the main reasons the drug remains in testing

Several factors influence why the BUD is shorter than a branded expiration date: Sterility concerns: Once a sterile vial is prepared, there is a finite window before the risk of microscopic bacterial growth increases

This phase is highly individualized and requires careful observation

Ayton et al., 2024)