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The FDA has not approved any GLP-1 weight loss patches yet because of the skin-penetration challenge
Gut metabolome changes translated to systemic circulation with lower levels of serum kynurenine, kynurenine/tryptophan ratio, and kynurenic acid/kynurenine ratio
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Neither has been formally tested in a clinical trial comparing the two
The second is Zepbound
And spoiler alert: Theyre really not into this trend
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