switching from dulaglutide to semaglutide Dulaglutide, #semaglutide, and #tirzepatide showed similar #gastrointestinal safety profiles in this population of type 2 diabetes patients in clinical settings. https://f.mtr.cool/ooyqaxfvpk Frontiers | Tolerability and Effectiveness

This means insulin is released only when blood glucose levels are elevated, reducing the risk of hypoglycaemia

"A role for the melanocortin 4 receptor in sexual function"

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Tirzepatide 15 mg (the highest available dose) was the most effective in lowering A1c versus placebo (mean difference [MD], 2%, 95% CI -2.16 to -1.84), followed by tirzepatide 10 mg (MD -1.86%, 95% CI -2.02 to -1.84) and semaglutide 2 mg (MD, 95% CI -1.62%, -1.96 to -1.28)

Mitten, Piero Portincasa, Gyorgy Baffy eClinicalMedicine .2026

Early and late-stage clinical trial coverage has reported major weight-loss results, and some discussions have focused on whether retatrutide may help support better body composition during weight loss