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Obesity is a chronic disease caused by various causes [12,13]
Oral administration does not work: digestive enzymes destroy the peptide before absorption, leaving bioavailability below 5%
Improvements are minimal as compared to surgery
Patients with known genetic causes should undertake lifestyle changes to avoid circumstances known to trigger rhabdomyolysis (39)
Nagashima M, Watanabe T, Terasaki M (2011) Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice
The Bigger Picture: Food, Inflammation, and Health To understand GLP-1 weight loss drugs and migraines in context, it helps to look at the broader system we all live in
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