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Genetic factors may also influence the glycaemic response to GLP-1 RAs, although their impact is uncertain, while a genome-wide study did not find a link between genetic variants and weight loss response to this drug class [3], suggesting that different mechanisms are involved in the glycaemic and weight loss effects of GLP-1 RAs
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Microbiome-targeted therapeutic interventions such as prebiotics, probiotics, and fecal microbiota can be promising as an adjunctive treatment for depression disorder
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