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Accumulated evidence suggests that long term treatment with GLP-1 receptor agonist is associated with a reduction in measured glomerular filtration rate (GFR), preservation of renal function and/or a decrease in the incidence of cardiovascular events
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They can adopt various phenotypes, such as the inflammatory-promoting M1 subtype and the inflammation-suppressing M2 phenotype, and secrete different inflammatory mediators in response to inflammation [102,103,104]
A 1mg dose showed 42.9%, at a 4mg dose, a 57% and at an 8mg dose showed an 81.4% reduction, and a 12mg dose showed an 82.4% reduction of liver fat at 24 weeks
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Commonly marketed under brand names like Ozempic and Wegovy, these medications are often hailed as "miracle drugs" for their transformative effects on weight loss and overall health
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