When macrophages encounter efferocytic stimuli, glucose is preferentially shunted to the PPP to counter the oxidative stress caused by efferocytosis
developed a novel hypoxia-activated combination nanomedicine that targets hypoxic tumors through hypoxia-sensitive block copolymers and photothermal/photodynamic therapy (PTT/PDT), efficiently delivering drugs and achieving synergistic anticancer effects of chemotherapy and PDT/PTT, completely eliminating advanced breast cancer, including hypoxic and metastatic tumors, stimulating a systemic antitumor immune response, and significantly improving survival rates, showing important clinical application potential [500]
Nutrients , 11 (9), 2073.
Cells treated with test compounds were washed with PBS and incubated with 10 M 2,7-dichlorofluorescein diacetate (DCFH-DA) at 37 C for 30 min, followed by washing with PBS, digestion with trypsin, and collection
Each batch is verified through third-party testing, including mass spectrometry analysis confirming the molecular weight of 391.4 Da and structural identity
Women often experience hot flashes, sleep problems, mood changes, and weight gain during this time due to changes in hormones