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However, the underlying biochemical patterns remain unclear, and researchers continue to treat these outcomes cautiously
Figure 4 In the process of aging, the immune system of the skin will inevitably be affected, leading to its aging
PMC 6721828
it is also crucial for detoxification and cellular health
16 SIRT1 is broadly expressed in metabolically active tissues 17 and regulates lipid metabolism, 18 mitochondrial maintenance, ROS clearance, autophagy, and immune balance by deacetylating key transcriptional regulators, including peroxisome proliferator-activated receptor gamma coactivator 1- (PGC-1), Forkhead Box O (FOXO), and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) and p53
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