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doi: 10.3109/00498254.2013.820006 205 CampbellSDde MoraisSMXuJJ

Melatonin as a potent and inducible endogenous antioxidant: synthesis and metabolism

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2.2.3 Impact of vitamin D on progression of oral carcinogenesis Vitamin D exerts an oncostatic effect on pathogenesis of certain oral cancer, though the researches are still at a nascent phase

The changes appear natural, not sudden, because they come from deep repair rather than surface-level lightening