Semaglutide itself doesnt deplete any specific nutrientsbut if youre eating less overall , your intake of essential vitamins and minerals may naturally drop
Its also crucial to start with a low dose and increase gradually as instructed by a healthcare professional
Between those extremes is a widening gap
Tantibhadrasapa A, Li S, Buddhasiri S, Sukjoi C, Mongkolkarvin P, Boonpan P, Wongpalee SP, Paenkaew P, Sutheeworapong S, Nakphaichit M, Nitisinprasert S, Hsieh MH, Thiennimitr P (2024) Probiotic Limosilactobacillus reuteri KUB-AC5 decreases urothelial cell invasion and enhances macrophage killing of uropathogenic Escherichia coli in vitro study
These findings are consistent with indirect comparisons from network meta-analyses and systematic reviews, which generally report superior weight-loss outcomes with tirzepatide compared with GLP-1 receptor agonists alone
For most people, this single-instance disruption is clinically insignificant