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Furthermore, DNA flow cytometry analysis in this study proved that AC arrested the leukemia cell cycle progression at the G1 phase through the inhibition of cyclin-dependent protein kinases CDK2, CDK4, and CDK6 activities and the upregulation of the CDK inhibitors, including p21 CIP1/WAF1 and p27 KIP1 (Lee et al
Zaki, Guido Bocci Journal of Oncology.2021
2015;10:e119857
Chemical stress is a by-product of exposure to or ingesting toxins or pollutants
& Gunnlaugsson, T
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