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With knee pain, extra weight can add stress to weight-bearing joints and make stairs, walking, and exercise feel more challenging
Reduced total body water means reduced CSF production (the choroid plexus produces CSF at a rate proportional to plasma volume)
This selectivity reduces off-target hormonal effects compared to broader secretagogues, making it useful in research and clinical exploration contexts
Kabel et al
22 , 11911200.e1315 (2010)
All the authors read and approved the final manuscript before submission
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