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Large doses of B12 can trigger acne-like symptoms in a small percentage of people
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655 In addition to its role in glycolysis and ATP production, PKM2 also regulates the redirection of glycolytic intermediates to the pentose phosphate pathway, thereby generating NADPH, which is critical for cellular redox homeostasis, 656 thus shielding cancer cells from oxidative stress
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GLP-1RAs normalize insulin resistance, and can also modulate dopaminergic signaling and reduce anhedonia, and their effects on glycemic variability and food cravings suggest potential use in addictive disorders
Interestingly, in a study by Wentzel et al
