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Further analysis of eQTLs highlighted 4 potential drug targets, including EDEM3, PBX3, MEIS1-AS3, and NME7
Thereafter, sections were incubated for 2 h at room temperature in the dark with Texas Red (Thermo Fisher Scientific)-conjugated (AR) and fluorescein isothiocyanate (Thermo Fisher Scientific)-conjugated (Prrx1) species-appropriate secondary antibodies, both diluted 1:100 in 1% horse serum
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Since tirzepatide inherently slows gastric emptying as part of its mechanism of action, administering it to patients with pre-existing gastroparesis could potentially worsen their condition and lead to severe gastrointestinal complications
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