However, potential adverse mental health effects have also been reported and require vigilance: Nausea and gastrointestinal symptoms , common side effects of GLP-1 medications, may increase anxiety in susceptible individuals Rapid weight loss can occasionally trigger psychological distress or exacerbate eating disorder behaviours Mood changes , including low mood, have been reported in post-marketing surveillance, though causality remains uncertain Some patients report feeling emotionally flat or detached , though this is anecdotal and not well characterised in clinical trials The Summary of Product Characteristics (SmPC) for GLP-1 receptor agonists used for weight management (such as Saxenda and Wegovy) includes specific warnings about monitoring for mood disorders and suicidal thoughts

So, its not surprising that they carry this risk of suicidal ideation but it doesnt mean that the drugs are unsafe. The FDA lists multiple GLP-1 drugs under review for safety on Suicidal thoughts are not currently listed as a potential side effect of Ozempic and Wegovy, according to the FDAs drug label and the EU product information
4 GWAS of side effects while on GLP-1 medication
Kuan C-H, Chang L, Ho C-Y, Tsai C-H, Liu Y-C, Huang W-Y, et al
No, never change your anticoagulant or antiplatelet medication dosing or timing for injections
This creates one additional consideration around alcohol