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La recherche suggre que le glutathion peut inhiber une enzyme en surface de la peau responsable des taches
J Physiol Pharmacol 2000
2024;7(2): e2355307
Patients with vitiligo have been found to have not only significantly increased average levels of hydrogen peroxide (H 2 O 2 ) in their skin lesions, but also significantly lower measured activities of catalase, superoxide dismutase, glutathione peroxidase and glutathione S-transferase than in the control group, as well as significantly increased levels of malondialdehyde [9, 15, 16]
Patients with a specific form of familial hypercholesterolemia not due to mutations in the LDLR gene were shown to have severe hypercholesterolemia due to mutations in the PCSK9 gene resulting in hyperactivity (gain-of-function mutations) of the enzyme
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