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Are GLP-1based injections safe

Collectively, the strong neuroanatomical enrichment of PDE1B and PDE10A within schizophrenia-relevant neuronal circuits, coupled with supportive preclinical evidence for PDE1B and more advanced clinical pharmacology for PDE10A, provides a compelling rationale to prioritize these isoforms over PDE2, PDE4, PDE8, and PDE9 in schizophrenia drug development

Miao XY, Gu ZY, Liu P et al (2013) The human glucagon-like peptide-1 analogue liraglutide regulates pancreatic beta-cell proliferation and apoptosis via an AMPK/mTOR/P70S6K signaling pathway

Key takeaways Both peptides boost growth hormone naturally, but Ipamorelin targets specific receptors while Sermorelin mimics natural hormone release

Metformin: Update on mechanisms of action and repurposing potential

Take your weight in kilograms and divide it by your height in meters squared