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The desalted sample was evaporated to dryness in a speedvac and then resuspended in 10 L Buffer A and analyzed by mass-spectrometry using the following LC-MS gradient: 5% buffer B in buffer A from 0-15 min, 515% buffer B from 1517.5 min, 1535% buffer B from 17.592.5 min, 3595% buffer B from 92.595 min, 95% buffer B from 95105 min, 955% buffer B from 105107 min, and 5% buffer B from 107125 min
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Most studies used doses between 1,0003,000 mg per day
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These agents play a critical role in regulating postprandial glucose levels by enhancing glucose-dependent insulin secretion, a mechanism that ensures precise control of blood sugar following meals
Research shows that by week 6, approximately 65-70% of patients report noticeable improvement in how they tolerate the drug
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