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5.3 Diabetic Retinopathy Complications In a pooled analysis of glycemic control trials, patients reported diabetic retinopathy related adverse reactions during the trial (4.2% with semaglutide tablets and 3.8% with comparator) [see Adverse Reactions (6.1)]

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in other words, it is only efficacious if it is also bioavailable, the researchers wrote

The GRADE evaluation of the evidence retrieved for the primary endpoint (HHF