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We found that tamoxifen at concentrations, which accumulate in tumors during therapy, increases oxidative stress in ER-positive and ER-negative breast cancer cells, resulting in cell death

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Understanding how peptides work at molecular levels provides biological plausibility and guides protocol development, but clinical validation through human trials remains essential for proving real-world benefits

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Earlier studies showed that in the 3x-Tg mice, LTP is reduced at 6 months of age before the development of plaques and tangles

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