For OB cFos image analysis, a custom-made pipeline (CellPofiler software) was used to automatically quantify cFos+ nuclei within the MCL
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In recent years, studies have found that the expression of GLP-1R is also found in liver and adipose tissue (Fig
What this trial could tell us If results are positive, we would expect to see statistically significant differences between the resM group and placebo group in body weight, BMI, and relevant biomarkers like fasting glucose, insulin, and possibly GLP-1 levels
We found that GEP12 functioned as a GLP-1R agonist with an EC 50 of 17.3 nM (Fig
During this procedure, an organic phase solution containing amphiphilic molecules is mixed with a solution containing the compounds to be encapsulated and then subjected to sonication