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Pathway inhibitor or treatment control when applicable

We gave daily intraperitoneal injections of sorafenib (30 mg/kg of body weight) to C57BL/6 mice for 2 weeks, simulating clinical doses

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In research settings semaglutide is studied for its activity at the GLP-1 receptor in cell-based metabolic and incretin-pathway models

The brain, despite representing only about 2% of body weight, consumes approximately 20% of the body's oxygen, generating substantial oxidative stress as a byproduct of its high metabolic activity