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Therefore, it is possible that overexpression of PGC-1 not only induced a faster metabolization of the drug, with a concomitant accumulation of highly reactive intermediates, but also contributed to a rapid GSH depletion by Glutathione S-transferases
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Sustained heart-rate elevation matters as cardiac load, not as a meaningful contribution to daily energy expenditure
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Laboratory research record on GLP-1S [PMID: 34192446] PubMed laboratory record discussing GLP-1S in a research context
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