GIP PHYSIOLOGY: SIMILARITIES AND DIFFERENCES WITH GLP-1 GIP is a 42-amino acid peptide secreted from intestinal K cells that are located mainly in the proximal small intestine
Both medications can lead to weight reduction, albeit through entirely different pharmacological pathways
12 Furthermore, postmarketing reports of acute pancreatitis, both fatal and nonfatal hemorrhagic and necrotizing, and rare hypersensitivity reactions such as angioedema and Stevens-Johnson syndrome may limit use in certain populations
This study is also reported in accordance with ARRIVE guidelines
Once they saw that exendin-4 interacted with the same cell receptors as GLP-1, they tested exendin-4 in diabetic rats, mice, and monkeys
Brand-name medications like Mounjaro can be expensive, especially without insurance