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675 Although the above small molecule compounds can prevent iron overload-related diseases by regulating iron metabolism, only DFO, DPF, and DFX are currently approved for clinical use

Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation

Cell Metab (2016) 24:55565

Figures also show that an estimated 300,000 tendon and ligament repair surgeries are performed annually in the US alone (Pennisi 2002)

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