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Potential side effects include injection site reactions (redness, swelling, pain), mild nausea (rare), headache (uncommon), fatigue (rare)

2005;63(2):S4878

GHK-Cu exerts broad anti-inflammatory effects through its influence on approximately 31% of the human genome, specifically downregulating genes involved in inflammatory processes including interleukin-1, tumor necrosis factor-, and nuclear factor-B (NF-B) signaling while upregulating protective genes encoding antioxidant enzymes, DNA repair proteins, and anti-inflammatory mediators

Interestingly, Epitalons effects appear to vary based on the biological age of the subject

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An equal amount of HIS-LET7 and HIS-LET7 K59D was incubated with GST-HOP1 glutathione beads for pull-down assays