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There is limited research on the head-to-head comparison of cardioprotective effects of GLP-1RAs and SGLT2 inhibitors, and the reason(s) for the similarity in the cardioprotective effect of these drug classes is not fully understood

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Subsequently, 200 L of lysis buffer was added to the pellet, and the cells were disrupted on ice with an ultrasonic cell disruptor for 5 min

Tirzepatide is a synthetic 39-amino acid peptide that acts as a dual agonist at both the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors

Exclusivity is a multi-layered construct: CoM patents, secondary thickets, and FDA regulatory exclusivities (NCE, ODE, pediatric) all contribute, and their interactions determine the total exclusivity duration