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doi: 10.1186/s12967-021-02817-2 33
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One potential mechanism is that H 2 S 2 and H 2 S 3 produced by 3MST readily react with free cysteine and GSH to produce Cys-SSH and GSSH, and react with cysteine residues of proteins to generate persulfurated proteins (Figs 2 and 8a)
GCN2 represses general protein synthesis and activates the transcription of genes involved in the synthesis and transport of amino acids via activation of ATF4 transcriptional factor
The Journal of Clinical Endocrinology & Metabolism, 75 (2), 530-535
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