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It always got worse. Then last May, Massarone was living in a sober home in Providence while serving probation, when a representative from Open Doors suggested a medication similar to Ozempic

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When testing each drug type separately, we estimate the effect of the SNP on BMI % to be larger in tirzepatide (effect = 0.95%) than semaglutide (effect = 0.51%), although the 95% confidence intervals were overlapping (Extended Data Fig

Crucially, these outcomes challenge the stereotype that obesity is simply a lifestyle choice

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Keep a food diary to spot personal triggers