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The long half-life provides a safety net for occasional missed doses, but optimal results require regular weekly injections

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[2] [4] Tirzepatide may cause fetal harm and should be avoided during pregnancy

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Leading obesity medicine societies now classify obesity as a chronic disease, and GLP-1 treatment as potentially long-term management, similar to statins for cholesterol or antihypertensives for blood pressure

GIP supports insulin sensitivity and may enhance appetite-suppressing effects when paired with GLP-1 activation