Although large-scale clinical trials are still lacking, multiple human and human-cell studies support IGF-1s role in tissue repair, hypertrophy, and metabolic balance
Lucarini, M., Luppi, B., Pedulli, G
Indeed, Garvey et al
These include: Enhanced glucose-dependent insulin secretion Suppressed glucagon secretion Slowed gastric emptying Increased satiety via central hypothalamic action This results in both glycaemic improvement and clinically meaningful weight loss
This is why the best formulations include ingredients that support absorption
Dose, duration, adherence, and changes in other medications over time are also important unanswered issues. Researchers say randomized clinical trials will be needed to confirm the findings and better understand how GLP-1 medications may affect cardiovascular risk in people with autoimmune diseases