They tried a few tricks: DPP-4-resistant versions: tweaking the GLP-1 molecule so DPP-4 cant see where to cut it Fatty acid tails: causing the GLP-1 to latch onto albumin in your blood, hiding from DPP-4 Encapsulation: wrapping the molecule in protective coatings so it survives longer before being exposed to enzymes These hacks meant the drug could hang out in the bloodstream for hours, or even days, instead of minutes
For example, in a study conducted by Nathanson et al
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Documented protocols maintain a fasted state for optimal GH response, and community sources describe running each peptide separately first to assess individual response before combining
Start: 100 mcg each peptide daily
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