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While the rare risk of medullary thyroid cancer requires a cautious approach for those with a specific family history, these medications offer a potentially transformative path for many who have struggled with weight for years

Similarly, epidemiological studies have captured a preventive effect, wherein individuals taking semaglutide for metabolic reasons exhibit a reduced risk of developing dementia

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Using both pharmacological and genetic approaches, we demonstrated that liraglutide retained antidepressant efficacy in GLP-1R antagonist-Exn9-treated mice or in Glp1r / mice, whereas gut microbiota depletion abolished its effects

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