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Robert Goldman MD, DO, PhD, FAASP Worldhealth.net A new phase 3 trial published in The Lancet reveals that #retatrutide, a nextgeneration GLP3 #agonist, may outperform todays GLP1 drugs in both #diabetes control and weight loss

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However, overuse can cause unintended issues

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When GLP-1 reaches the pancreas, it binds to the GLP-1 receptors (GLP-1R) expressed on pancreatic cells, stimulating insulin release

R., Jurvansuu, J