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Rheumatol Int 34:10531057
Safety concerns also surfaced: the FDA has linked compounded semaglutide to adverse events, including dosing errors that led to hospitalizations and, in certain cases, more serious outcomes
As there was clear evidence of clinically significant weight loss from the Phase III trials, tirzepatide has been planned to be evaluated as an anti-obesity drug in non-diabetic (SURMOUNT 1 trial), and diabetic (SURMOUNT 2 trial) populations, and on those who are already on intensive lifestyle programmes (SURMOUNT 3 trial)
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