Specifically, the label states these medications should be used in combination with a reduced calorie diet and increased physical activity. HaVy Ngo-Hamilton, PharmD, pharmacist and clinical consultant for BuzzRx, states that the amount of diet and exercise will vary among users, leading to various degrees of weight loss
Who is eligible to use oral semaglutide for weight management
Interestingly, patients receiving tirzepatide report reduced overall GI AEs (40%), nausea (17.4%), diarrhea (13.2%) and vomiting (5.7%) compared to patients on semaglutide (43%, 19.2%, 13.7%, and 8.1% respectively)
Both of these forms are composed of similar active pharmaceutical ingredients
PMC Cognitive Function and Neurological Research Robillard JM, et al
It makes it a well-designed observational finding rather than proof, and it means the question remains genuinely open until a randomized trial answers it