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These structural changes extend the drugs activity in the body, enabling less frequent dosing while maintaining its therapeutic effect

doi: 10.1038/s41467-023-41626-7 45 BersukerKHendricksJMLiZMagtanongLFordBTangPHet al

MD simulations were performed using the GROMACS 2018 package 41 with isothermalisobaric (NPT) ensemble and periodic boundary condition

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