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Vitamin D regulates LL-37 production, which partly explains why vitamin D analogs have some efficacy in psoriasis treatment and why sun exposure often improves symptoms

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It acts as a free radical scavenger, upregulating antioxidant enzymes such as superoxide dismutase and catalase (9)

However, ACV can be responsible for renal cytotoxicity with acute renal failure requiring dialysis (Neto et al., 2007)

Chondrogenic factors are secreted at the site of damage

Copper-zinc superoxide dismutase connects it to antioxidant capacity